Web Application Project is configured to use IIS. You do not have permission to access the IIS configuration file.

Error:

When trying to load web projects in Visual Studio, you get the following error…

Soution:

Browse to C:\Windows\System32\inetsrv and then double-click the “config” directory.

Do the same for the C:\Windows\System32\inetsrv\config\export directory and also the other directories in C:\Windows\System32\inetsrv.

Now you will be able to open the Visual Studio Web Application Project without a problem.

Source:

https://weblogs.asp.net/jeffwids/web-application-project-is-configured-to-use-iis-unable-to-access-the-iis-metabase